「~のメカニズム」というときも、ofとforの両方があり得ます。この使い分けはどうでしょうか。role of 、 role forの時と同じ感覚で使い分けができそうです。
たまたま検索でヒットした論文、
Molecular Mechanisms of Fear Learning and Memory (文献 Cell)
論文のタイトル「恐怖学習と恐怖記憶の分子メカニズム」ではofが使われています。要旨の中の文もof。
Pavlovian fear conditioning is a particularly useful behavioral paradigm for exploring the molecular mechanisms of learning and memory because a well-defined response to a specific environmental stimulus is produced through associative learning processes. (中略)
Collectively, this body of research illustrates the power of fear conditioning as a model system for characterizing the mechanisms of learning and memory in mammals and potentially for understanding fear-related disorders, such as PTSD and phobias.
本文に入ると最初はforが使われています。
LTP has provided a rich array of candidate mechanisms for the plasticity processes that could occur during actual fear learning but will not be the focus of this Review.
(中略)以下、mechanisum of/forが出てくる箇所を列挙します。
Molecular mechanisms of fear extinction will not be discussed here (for reviews, see Myers and Davis, 2007, Quirk and Mueller, 2008, Sotres-Bayon et al., 2006, Herry et al., 2010, and Pape and Pare, 2010).
We thus start our exploration of the cellular and molecular mechanisms of fear memory formation by considering the acquisition/training phase of fear conditioning during which learning occurs.
This provides a potential alternate mechanism for NMDAR activation during fear learning that is non-Hebbian in nature (i.e., does not require postsynaptic depolarization) and should be taken into consideration when discussing the effects of pharmacological manipulations of the NMDAR in the LA.
Supporting this as a mechanism for fear learning, GluA1 is increased in the LA following fear conditioning and is required for fear memory formation.
Although the mechanism of β-AR involvement in the acquisition of fear learning is unclear, one possibility is that they act on GABAergic interneurons to suppress feed-forward inhibition and enhance Hebbian plasticity mechanisms.
Though the mechanisms for this are not completely understood, it appears that PKMζ maintains fear memories by reducing GluA2 AMPAR subunit removal from synapses and thereby sustaining the synaptic strengthening originally induced by fear learning
Our understanding of the cellular and molecular mechanisms of memory reconsolidation is at an early stage.
Thus, we will focus specifically on the molecular mechanisms of auditory fear memory reconsolidation in LA neurons.
Understanding the mechanisms of this process is appealing both for understanding how memories are encoded in the brain and because it could provide new treatment avenues for debilitating memory-related disorders such as PTSD.
Thus, we demonstrate a heretofore unknown molecular mechanism for cough induction by a virulent human pathogen via its production of a complex lipid. (論文Cell)
Our structure supports the classical “sliding helix” mechanism of voltage sensing and provides a complete gating mechanism for voltage sensor function, pore opening, and activation-gate closure based on high-resolution structures of a single sodium channel protein. (論文 Cell)
Figure 6 Gating Mechanism for Voltage-Gated Sodium Channels(論文 Cell)
3.3 Å Cryo-EM Structure of a Nonenveloped Virus Reveals a Priming Mechanism for Cell Entry(論文 Cell)
Our experiments establish a mechanism for ICL repair that reveals how this process is coupled to DNA replication. (論文 Cell)
We propose that a two-stage mechanism of signal-driven insertion into a membrane protein complex and subsequent integration into the lipid phase may represent a general mechanism for biogenesis of β-barrel proteins.(論文 Cell)
のようになることが多いようです。ofとforの使い分けは前後の言葉や文脈で決まるため、一つの文章中で両方が混在することが普通に起こります。未知か既知かというニュアンスの違いがあるので、一度未知なものとしてa role for~と読者に紹介されたあとは、それ以降、既知になるのでthe role of~と自然に変わるわけです。パターンで覚えるのは無意味で、あくまで文脈に応じた使い分けが必要になります。
具体例を見ていきましょう。グーグル検索でたまたまヒットした論文ですが、
A human ESC-based screen identifies a role forthe translated lncRNA LINC00261 in pancreatic endocrine differentiation (文献リンク eLife)
論文のタイトル中では、「翻訳された長鎖ノンコーディングRNA LINC00261の役割」というときにa role forが用いられています。これは今まで知られていなかった役割を見出したという文脈だからforです。
Our comprehensive assessment of functional lncRNA translation identified a likely trans-regulatory role forLINC00261 in endocrine cell differentiation that appears to be independent of the seven microproteins that were individually deleted.
ここでもa ~ role for ~ という形が使われています。ところが、今度は、
To identify potential functional roles of translated lncRNAs during pancreas development, we selected ten candidates for CRISPR/Cas9-based genome editing in hESCs through excision of the lncRNA promoter or entire lncRNA locus (Figure 3A,B).
Trans-regulatory roles of LINC00261 have also been observed in previous studies.
ここでもofですが、これはこの役割があることを前提とした文脈だからです。
These results indicate that there is not one dominant LINC00261 sORF that is required for endocrine cell formation, suggesting a functional role of the LINC00261 transcript and not the individual sORFs mutated here.
ここもofが使われています。
In this study, we have characterized the role of translated lncRNAs.(本研究では翻訳される長鎖ノンコーディングRNAの役割を解析した。)
Condensed Conjugation Molecular Physics and Chemistry: Revisiting “Electronic Conjugation” Leading to Innovative Physical Properties of Molecular Materials
“Go To Travel” Campaign and Travel-Associated Coronavirus Disease 2019 Cases: A Descriptive Analysis, July–August 2020 by Asami Anzai and Hiroshi Nishiura (Journal of Clinical Medicine, MDPI)
西浦教授が「Go To トラベル研究」への批判に答える (1/29(金) 8:00配信 m3.com)
Go Toキャンペーン論文がMDPIジャーナルに掲載されたものであったことで、ネット上が騒がしくなったようです。「 MDPIはハゲタカジャーナルか?」に書きましたが、MDPIジャーナルはハゲタカジャーナルだと断定的に言うことはできません。査読が非常にゆるい雑誌が多いことは間違いありません(全てかどうかはわかりません)。査読がゆるいと言っても決して査読者がいい加減に査読しているわけではありません(自分も査読経験あり)。採否を決めるのはジャーナルのエディターなので、査読者が真面目に論文を読み込んで、どれほど厳しい要求をしたところで、エディターがビジネス優先で、「いいよ、いいよ、これで。」と言えば、どんな論文でも掲載されてしまうのです。
MDPIジャーナルは査読者に一週間以内に査読コメントを返すように要求してきたりします。
We have received the following manuscript to be considered for publication in International Journal of Molecular Sciences
(https://www.mdpi.com/journal/ijms/) and kindly invite you to provide a review to evaluate its suitability for publication:
(中略)
If you accept this invitation we would appreciate receiving your comments within 1 week. Please let us know if you will need more time.
定員が150人ほどで、お茶の水校にしかないコースのため大変人気となっています。私は後期日程の結果を見てから駿台の説明会に行ったので、希望していた「東大理系演習コース」は締め切っていましたし、代替案としての駿台横浜校の東大理系コースも定員が埋まっていました。(駿台お茶の水校3号館理系コースな一年 簡単に振り返り Posted on March 5, 2020 チラ裏の宝石箱)
一番東大合格に近いコースなので一番人気があり、希望者がみな入れるわけではないということのようです。
スーパー東大理系演習コースに向いている人・向いていない人
きちんと自分のレベルを知ったうえでコースを選ばないと痛い目にあいます。演習コースでも落ちる人は落ちますし、通常コースでも受かる人はたくさんいます。(【浪人経験者が語る】駿台での浪人生活ってどんな感じ?|生活編 LIFE 2020.04.14 2019.05.18)
Active seating, Tic Toc – Fully 2018/04/18 Fully
Designed by our founder and CEO, David Kahl, along with Hans Christian Mengshoel, legendary designer of the Balans sitting concept and original kneeling chair, Tic Toc helps your body find its natural rhythm.
An activating platform is disclosed. The platform includes a base that has a lower surface that is curved in a direction transverse to a longitudinal axis. The curved shape of the base provokes a user rock around in a small angle around a middle position, thereby promoting active sitting. (Inventors: Mengshoel; Hans Christian United States Patent 10,595,640)
① 結婚相手として希望する条件を明確にする(自分を知る)・重要度マトリクス分析 ② 婚活における現状が適切であるかを把握する(現状を知る)・婚活のMLVP分析 ③ 求める相手と結ばれるために足りないものを見つけて埋める・プロセスマップ分析 ④ 常に前進する、成長する・PDCA(G) 分析(徹底的に婚活すると決意したあなたに読んでほしい「ホワイトマリッジ婚活フレームワークメソッド」2019.12.29 婚活ブログ)
Oxytocin is released at orgasm and is associated with both sexual pleasure and the formation of emotional bonds.[15] (Wikipedia)
A key hormone released during sex is oxytocin, also known as the ‘cuddle hormone’. … It’s also the key to bonding, as it increases levels of empathy. Women produce more of this hormone, although it’s not clear why, and this means they are more likely to let their guard down and fall in love with a man after sex. However, the problem is that the body can’t distinguish whether the person we’re with is a casual fling or marriage material — oxytocin is released either way. (Sex: Why it makes women fall in love – but just makes men want MORE! By ANNA HODGEKISS UPDATED: 22:02 GMT, 29 August 2011 Mail Online)
Researchers in one 2012 study found that couples in the first stages of romantic attachment had significantly higher levels of oxytocin than their unattached counterparts.
One 2013 review summarized all of oxytocin’s possible relationship-enhancing effects.
(Why Is Oxytocin Known as the ‘Love Hormone’? And 11 Other FAQs healthline.com)
The orgasmic history of oxytocin: Love, lust, and labor. Indian J Endocrinol Metab. 2011 Sep; 15(Suppl3): S156–S161. doi: 10.4103/2230-8210.84851. PMC3183515
The impact of sexual activity on endogenous OXT release is informed by numerous studies showing increased OXT plasma concentrations after orgasm in humans (67–70) [but see also (71)].
67. Ogawa S, Kudo S, Kitsunai Y, Fukuchi S (1980): Increase in oxytocin secretion at ejaculation in male. Clin Endocrinol (Oxf) 13:95–97.
68. Carmichael MS, Warburton VL, Dixen J, Davidson JM (1994): Relationships among cardiovascular, muscular, and oxytocin responses during human sexual activity. Arch Sex Behav 23:59–79.
69. Murphy MR, Checkley SA, Seckl JR, Lightman SL (1990): Naloxone inhibits oxytocin release at orgasm in man. J Clin Endocrinol Metab 71:1056–1058.
70. Blaicher W, Gruber D, Bieglmayer C, Blaicher AM, Knogler W, Huber JC (1999): The role of oxytocin in relation to female sexual arousal. Gynecol Obstet Invest 47:125–126.
71. Kruger TH, Schiffer B, Eikermann M, Haake P, Gizewski E, Schedlowski M (2006): Serial neurochemical measurement of cerebrospinal fluid during the human sexual response cycle. Eur J Neurosci 24:3445–3452.
Oxytocin is released at orgasm and is associated with both sexual pleasure and the formation of emotional bonds.[15] (Wikipedia)
A key hormone released during sex is oxytocin, also known as the ‘cuddle hormone’. … It’s also the key to bonding, as it increases levels of empathy. Women produce more of this hormone, although it’s not clear why, and this means they are more likely to let their guard down and fall in love with a man after sex. However, the problem is that the body can’t distinguish whether the person we’re with is a casual fling or marriage material — oxytocin is released either way. (Sex: Why it makes women fall in love – but just makes men want MORE! By ANNA HODGEKISS UPDATED: 22:02 GMT, 29 August 2011 Mail Online)(*太字強調は当サイト)